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FAQ
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What is peripheral blood?Peripheral blood refers to blood other than bone marrow blood. Peripheral blood is often used in clinical practice for blood routine, biochemistry, Serum immunoassays to diagnose or differentiate certain diseases, peripheral blood morphology and cytology The examination is important for the diagnosis of various blood diseases.
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What impact will the decline in immune cell activity have on the human body as people age?As we age, healthy immune cells in our bodies gradually degenerate, including changes in number, toxicity, and The decline of killing function, weakened signal transmission in cells, increased apoptosis, etc. make the elderly more susceptible to to bacterial and viral infections and cancer; maintaining or rebuilding proper immunity can prevent aging. The autologous immune cells stored in youth will become the future immune reconstruction or infection and The most valuable biological resource for cancer immunotherapy.
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What are autologous immune cells? How are they different from allogeneic immune cells?Autologous immune cells refer to cells that are present in the body itself and are not introduced from foreign bodies and are involved in or related to immune responses. Immune cells from outside the individual are called allogeneic immune cells. Allogeneic immune cells can also play a part in immune function, but may produce rejection reaction with autologous cells, which poses a safety hazard. Immunity care or treatment all use autologous immune cells as the basis.
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What is the approximate proportion of various immune cells to the total number of lymphocytes in peripheral blood?(1) The normal white blood cell count in an adult's peripheral blood is 400 million to 1 billion/L; (2) NK cells account for approximately 8%-15% of the total lymphocytes in peripheral blood; (3) B cells account for approximately 10%-15% of the total lymphocytes in peripheral blood; (4) T cells account for approximately 65%-75% of the total lymphocytes in peripheral blood.
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What is the function of each major immune cell in the body?NK cells: Natural killer cells (NK cells) originate from bone marrow lymphoid Stem cells, whose differentiation and development depend on the bone marrow and thymus microenvironment, are mainly distributed in the bone marrow, peripheral blood, liver, Spleen, lungs and lymph nodes. It does not need to receive special instructions from the immune system, nor does it require the cooperation of other cells. It can identify and eliminate pathogenic microorganisms by itself. It is a kind of Recall the "all-round" immune cells that have three major functions in one. T cells: lymphocyte stem cells derived from the bone marrow, which differentiate and mature in the thymus. It is distributed to immune organs and tissues throughout the body through blood circulation to exert immune functions. Functions, such as direct killing of target cells, assisting or inhibiting B cells to produce antibodies, specific antigens and mitogens The response to mitogens and the production of cytokines are the body's defenses against disease infection and tumors. The immune response produced by T cells is cellular immunity, and there are two main effector forms of cellular immunity: One is to specifically bind to the target cell, destroy the target cell membrane, and directly kill the target cell; the other is to release lymphocytes factors, ultimately expanding and enhancing the immune effect. DC cells: also called dendritic cells, are the most powerful professional antigen-presenting cells in the body. Effectively take up, process and present antigens. Immature DCs have strong migration ability. It effectively activates initial T cells and is at the center of initiating, regulating, and maintaining the immune response. B cells: B cells can differentiate into plasma cells under antigen stimulation, and plasma cells can synthesize and secrete antibodies (immune Immunoglobulin, which mainly performs humoral immunity. Activated B cells produce a large number of cytokines and participate in Immunomodulation, inflammatory response and hematopoiesis.
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How many cells does the human body have?The human body has approximately 40 trillion to 60 trillion cells.
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To what quantity level can NK cells from umbilical cord blood be cultured?3.5-5 billion.
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Why do some customers use umbilical cord blood NK cells instead of their own NK cells?1. Wide sources, easy to collect, low immunogenicity and good tissue compatibility; 2. The cell morphology is better than the original diseased body; 3. In cord blood, the number of NK cells is relatively high, about 3 times that of peripheral blood; 4. NK cells obtained from umbilical cord blood are younger, have stronger proliferation and more effective targeting; 5. It is more convenient to collect and cryopreserve NK cells from umbilical cord blood, but long-term cryopreservation will affect their proliferation potential. There was no significant effect on the potency and anticancer effect.
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How many immune cells are there in the human body? How many NK cells are there? What effect can the transfused NK cells achieve?(1) The total number of immune cells in the human body is between 3.5 billion and 9.5 billion per liter. Based on the blood volume of 5 liters, The body value is 17.5 billion-47.5 billion. (2) The number of NK cells is between 100 million and 400 million per liter. Based on the human blood volume of 5 liters, the specific value is 500 million to 2 billion (the value for healthy people). (3) The number of NK cells in our cell products is about 4-6 billion, which is at least the maximum number in a healthy person. The maximum value is twice, which is enough to break the original immune balance, eliminate inflammation in the body, regulate immune levels, and clear It can eliminate senescent cells and apoptotic cells, delay aging, and enhance overall immune function.
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What are immune cells?Refers to cells involved in or related to immune response, commonly known as "white blood cells", whose main function is to remove Including dendritic cells, monocytes/ Macrophages, granulocytes, mast cells, etc. Immune cells can be divided into many types, including innate lymphocytes, Various phagocytes and lymphocytes that can recognize antigens and produce specific immune responses play a role in the human body. It plays an important role in defense and protection, ensuring that the body is not invaded by pathogenic microorganisms such as bacteria, viruses, mycoplasma, chlamydia, etc. Biological invasion; prevent mutations and damage in the body from developing into chronic diseases or tumors. Currently stored immune cells It refers to the B cells, T cells, NK cells and other cell products obtained by separation and purification after peripheral blood extraction. Stored in liquid nitrogen at -196ÿ, cells can be revived in the future and used in the treatment of diseases and health of the body. Recovery, sub-health conditioning, elimination of body aging, etc.
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